Human iPSC-derived Cells and Drug Discovery
Kohei Sawada
Graduate School of Pharmaceutical Sciences
Laboratory of Human Cell-based Drug Discovery Project Professor
- Establish translational assay systems for efficacy/safety of medical-use drug candidates
- Develop devices, iPS cell products, culture medium and culture matrix
- Explore novel biomarkers using normal and disease human iPS-derived cells
- Conduct educational activities to promote knowledge, technology and application of iPS cells
- Establish the center for human iPS cell science by networking the academia, pharmaceutical companies and regulatory organizations
- Develop devices, iPS cell products, culture medium and culture matrix
- Explore novel biomarkers using normal and disease human iPS-derived cells
- Conduct educational activities to promote knowledge, technology and application of iPS cells
- Establish the center for human iPS cell science by networking the academia, pharmaceutical companies and regulatory organizations
Laboratory of Human Cell-based Drug Discovery
Laboratory of Human Cell-based Drug Discovery
Related links
- Under construction
Research collaborators
- Yokogawa Electric Corporation
- Asahi Glass Co.,Ltd.
- LSI Medience Cooperation
- Cellular Dynamics International Japan,Inc.（Fuji Film group company）
- Asahi Glass Co.,Ltd.
- LSI Medience Cooperation
- Cellular Dynamics International Japan,Inc.（Fuji Film group company）
Related publications
- Kimura T, Uesugi M, Takase K, Miyamoto N, Sawada K. Hsp90 inhibitor geldanamycin attenuates the cytotoxicity of sunitinib in cardiomyocytes via inhibition of the autophagy pathway. Toxicology and Applied Pharmacology. 2017; 329: 282-292.
- Fukushima K, Yamazaki K, Miyamoto N, Sawada K. Functional Characterization of Acetylcholine Receptors Expressed in Human Neurons Differentiated from Hippocampal Neural Stem/Progenitor Cells. J Biomol Screen. 2016; 21(10): 1065-1074
- Fukushima K, Miura Y, Sawada K, Yamazaki K, Ito M. Establishment of a Human Neuronal Network Assessment System by Using a Human Neuron/Astrocyte Co-Culture Derived from Fetal Neural Stem/Progenitor Cells. J Biomol Screen. 2016; 21(1): 54-64
- Asakura K, Hayashi S, Ojima A, Taniguchi T, Miyamoto N, Nakamori C, Nagasawa C, Kitamura T, Osada T, Honda Y, Kasai C, Ando H, Kanda Y, Sekino Y, Sawada K. Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes. J Pharmacol Toxicol Methods. 2015; 75:17-26
- Fukushima K, Yamazaki K, Miyamoto N, Sawada K. Functional Characterization of Acetylcholine Receptors Expressed in Human Neurons Differentiated from Hippocampal Neural Stem/Progenitor Cells. J Biomol Screen. 2016; 21(10): 1065-1074
- Fukushima K, Miura Y, Sawada K, Yamazaki K, Ito M. Establishment of a Human Neuronal Network Assessment System by Using a Human Neuron/Astrocyte Co-Culture Derived from Fetal Neural Stem/Progenitor Cells. J Biomol Screen. 2016; 21(1): 54-64
- Asakura K, Hayashi S, Ojima A, Taniguchi T, Miyamoto N, Nakamori C, Nagasawa C, Kitamura T, Osada T, Honda Y, Kasai C, Ando H, Kanda Y, Sekino Y, Sawada K. Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes. J Pharmacol Toxicol Methods. 2015; 75:17-26
Contact
- Yuji Ikegaya, Ph.D. / Kohei Sawada, Ph.D.
- Tel: +81-3-5841-4708 / +81-3-5841-4355
- Email: yuji[at]ikegaya.jp / k-sawada[at]mol.f.u-tokyo.ac.jp
※摆补迟闭=蔼
